Bioss Inc.'s Major Vault Protein (4G1) Monoclonal Antibody is a Rabbit monoclonal antibody. The Major Vault Protein (4G1) Monoclonal Antibody was generated using major vault protein, and MVP as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases